Alcohols and polyols

Organic compounds containing one or more hydroxyl functional groups bonded to a carbon atom; hydroxyls consist of an oxygen atom bonded to a hydrogen atom. Alcohols exist in chain, or as closed rings. Polyols contain two or more hydroxyl groups.

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4,846 – 4,860 of 5,342 results

4,846

Medchemexpress LLC Nevanimibe hydrochloride | 133825-81-7 | MFCD00899568 | 99.5% | 458.08 g/mol | C27H40ClN3O | 1 ML

Nevanimibe hydrochloride is the hydrochloride salt of nevanimibe, a selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor supplied as a 10 mM solution in DMSO (1 mL) for in vitro research use.

Selective ACAT1 inhibitor with low-nanomolar activity
Supplied as a ready-to-use 10 mM solution in DMSO
High purity (~99.5%) suitable for biochemical and cell-based assays
Molecular weight 458.08 g/mol aids solution preparation calculations
Available in solid and solution formats for flexibility in workflows

Pricing & Availability

4,847

Medchemexpress LLC Nordoxepin hydrochloride | 2887-91-4 | MFCD00135797 | 99.9% | 301.81 g·mol⁻¹ | C18H20ClNO | 1 ML

Nordoxepin hydrochloride is the hydrochloride salt of nordoxepin (desmethyldoxepin), the primary metabolite of the tricyclic antidepressant doxepin. It is intended for research and analytical applications and is supplied as a ready-to-use 10 mM solution in DMSO (1 mL) and in multiple solid mass formats for analytical and synthetic workflows.

High purity suitable for research applications (99.94%).
Supplied as a ready-to-use 10 mM solution in DMSO for convenient dosing.
Available in multiple solid mass sizes for synthetic and analytical work.
Molecular weight 301.81 g·mol⁻¹ and formula C18H20ClNO for easy reference.
Storage guidance: solid at 4°C; solution at -80°C (up to 6 months) or -20°C (up to 1 month).

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4,848

Medchemexpress LLC AMXI-5001 hydrochloride | 00-00-0 | 98.1% | C25H21ClFN5O3 | 10MG

AMXI-5001 hydrochloride is a research-grade small molecule described as a dual inhibitor of PARP1/2 and microtubule polymerization. It shows potent cellular activity against PARP and tubulin targets, with reported favorable metabolic stability and oral bioavailability, and is intended for preclinical anticancer research.

Dual mechanism: inhibits PARP1/2 and tubulin polymerization.
Potent PARP inhibition with low nanomolar IC50s and tubulin inhibition in the micromolar range.
Orally bioavailable with favorable pharmacokinetic properties.
Suitable for in vitro and in vivo anticancer studies.
High purity for research applications.

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4,849

Medchemexpress LLC Topotecan hydrochloride | 119413-54-6 | MFCD00866235 | 99.9% | 457.91 | 100 MG

Topotecan hydrochloride is a potent Topoisomerase I inhibitor with significant antineoplastic activities. It is intended for research and analytical applications, playing a role in studies related to cancer, autophagy, and apoptosis.

Potent Topoisomerase I inhibitor
Demonstrates antineoplastic activities
Inhibits the proliferation of human glioma cells
Induces cell cycle arrest in G0/G1 and S phases
Promotes apoptosis in various cell lines
Store at 4°C, sealed, away from moisture and light
Store in solvent at -80°C for 2 years or -20°C for 1 year

Pricing & Availability

4,850

Medchemexpress LLC Ladostigil hydrochloride | 209394-18-3 | 99.9% | 308.80 g/mol | C16H21ClN2O2 | 50 MG

Ladostigil hydrochloride is the hydrochloride salt of ladostigil, an orally active dual inhibitor of cholinesterase and brain-selective monoamine oxidase. It exhibits neuroprotective, antioxidant, and anti-inflammatory properties and is used as a research reagent in studies of neurodegeneration, depression, and Alzheimer's disease.

Dual cholinesterase and monoamine oxidase inhibitor
Neuroprotective, antioxidant, and anti-inflammatory activity
Hydrochloride salt for improved solubility
Click-chemistry compatible (contains an alkyne group)
High purity verified by RP-HPLC, suitable for research

Pricing & Availability

4,851

Medchemexpress LLC Sri-37330 hydrochloride | 2322245-49-6 | 99.72% | C16H20ClF3N4O2S | 1 G

SRI-37330 hydrochloride is an orally bioavailable thioredoxin-interacting protein (TXNIP) inhibitor. It inhibits glucagon secretion and function, reduces hepatic glucose production, and reverses hepatic steatosis. This compound can be used for type 2 diabetes research.

Inhibits human TXNIP promoter activity in INS-1 cells.
Decreases TXNIP mRNA and protein levels in INS-1 cells.
Blocks polymerase II binding to the E-box motif of the TXNIP promoter.
Reduces glucagon secretion in TC1-6 cells.
Inhibits glucagon-induced glucose output from primary hepatocytes.
Decreases glucagon secretion and action, and blocks hepatic glucose output in vivo.
Well tolerated in male C57BL/6J mice.
Reverses obesity- and STZ-induced diabetes and hepatic steatosis in mice.

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4,852

Medchemexpress LLC Fadrozole hydrochloride | 102676-31-3 | 99.9% | C14H14ClN3 | 1 ML

Fadrozole hydrochloride (CGS 16949A) is a potent, selective, and nonsteroidal aromatase inhibitor that effectively inhibits estrogen production. It is intended for research use only and not for patient use.

Potent and selective aromatase inhibitor with an IC50 of 6.4 nM.
Inhibits estrogen production in hamster ovarian slices with an IC50 of 0.03 μM.
Can suppress the synthesis of other cytochrome P-450 dependent steroids at higher doses.
Prevents the development of spontaneous mammary neoplasms in female rats.
Slows the development of pituitary pars distalis adenomas.
Reduces the incidence of spontaneous hepatocellular tumors.
Reduces parasite burden in male and female mice by 70%.

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4,853

Medchemexpress LLC AMXI-5001 hydrochloride | 98.1% | C25H21ClFN5O3 | 1 ML

AMXI-5001 hydrochloride is a potent, orally active, and dual PARP1/2 and microtubule polymerization inhibitor. It shows selective antitumor cytotoxicity across a wide range of human cancer cells with significantly lower IC50s compared to existing clinical PARP1/2 inhibitors, and can induce complete regression of established tumors, including very large ones.

Potent and orally active
Dual PARP1/2 and microtubule polymerization inhibitor
Selective antitumor cytotoxicity across a wide range of human cancer cells
Significantly lower IC50s compared to existing clinical PARP1/2 inhibitors
Induces complete regression of established tumors

Pricing & Availability

4,854

Medchemexpress LLC Abeprazan hydrochloride | 1902954-87-3 | 99.9% | 446.87 | 50 MG

Abeprazan hydrochloride (DWP14012 hydrochloride) is a potassium-competitive acid blocker that inhibits H+, K+- ATPase through reversible potassium-competitive ionic binding without requiring acid activation. It is being developed as a potential alternative to proton pump inhibitors for treating acid-related diseases.

Potassium-competitive acid blocker.
Inhibits H+, K+- ATPase by reversible potassium-competitive ionic binding.
Does not require acid activation for its inhibitory mechanism.
Developed as a potential alternative for proton pump inhibitors.
Inhibits acid secretion in a dose-dependent manner in in vivo studies.
Efficacy is equal to or greater than that of vonoprazan in various in vivo studies.

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4,855

Medchemexpress LLC AMXI-5001 hydrochloride | 98.1% | C25H21ClFN5O3 | 100 MG

AMXI-5001 hydrochloride is a potent, orally active, and dual PARP1/2 and microtubule polymerization inhibitor. It exhibits selective antitumor cytotoxicity across a wide variety of human cancer cells with much lower IC50s than existing clinical PARP1/2 inhibitors. This compound induces complete regression of established tumors, even very large ones. It is intended for research use only and not sold to patients.

Potent and orally active
Functions as a dual PARP1/2 and microtubule polymerization inhibitor
Demonstrates selective antitumor cytotoxicity against various human cancer cells
Has significantly lower IC50s compared to existing clinical PARP1/2 inhibitors
Induces complete regression of established tumors
For research use only

Pricing & Availability

4,856

Medchemexpress LLC CCG258208 hydrochloride | 98.1% | 488.94 | 1 MG

CCG258208 (GRK2-IN-1) hydrochloride is a potent and selective GRK2 (G protein-coupled receptor kinase 2) inhibitor (IC50=30 nM). It exhibits 230-fold selectivity over GRK5 and more than 2500-fold selectivity over GRK1, PKA, and ROCK1. This compound can be utilized in heart failure research.

Potent and selective GRK2 inhibitor (IC50=30 nM).
Exhibits 230-fold selectivity over GRK5 (IC50=7.09 μM) and more than 2500-fold selectivity over GRK1 (IC50=87.3 μM), PKA, and ROCK1.
Applicable in heart failure research.
Significant improvement in βAR-stimulated contractility in mouse cardiomyocytes at concentrations as low as 0.1 μM.
Superior half-life in vivo with total plasma drug levels exceeding the GRK2 IC50 for seven hours after a single intraperitoneal administration of 10 mg/kg in CD-1 mice.

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4,857

Medchemexpress LLC Gefitinib hydrochloride | 184475-55-6 | 99.8% | 500 MG

Gefitinib hydrochloride (ZD1839 hydrochloride) is a potent, selective, and orally active inhibitor of EGFR tyrosine kinase, with an IC50 of 33 nM. It specifically inhibits EGF-stimulated tumor cell growth with an IC50 of 54 nM and blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Additionally, Gefitinib hydrochloride has been shown to induce autophagy and possesses antitumour activity.

Potent, selective, and orally active EGFR tyrosine kinase inhibitor.
Inhibits EGF-stimulated tumor cell growth.
Blocks EGF-stimulated EGFR autophosphorylation in tumor cells.
Induces autophagy.
Demonstrates antitumour activity.

Pricing & Availability

4,858

Medchemexpress LLC Ninhydrin | 485-47-2 | 99.99% | 1 ML

Ninhydrin is a chromogenic analytical probe utilized for the quantification of amino acids and proteins. It is widely employed in amino acid analysis of proteins, where most amino acids, excluding proline, undergo hydrolysis and react with ninhydrin, allowing for their colorimetric quantification following chromatographic separation. Ninhydrin interacts with primary and secondary amines to yield a distinctive blue or purple reaction product, diketohydrindylidene-diketohydrindamine.

Functions as a chromogenic analytical probe.
Enables quantification of amino acids.
Facilitates quantification of proteins.
Reacts with most amino acids (excluding proline).
Permits colorimetric quantification post-chromatographic separation.
Interacts with primary and secondary amines.
Generates a blue or purple reaction product.

Pricing & Availability

4,859

Medchemexpress LLC Tocainide hydrochloride | 71395-14-7 | 99.5% | 1 ML

Tocainide hydrochloride is a sodium channel blocker that blocks sodium channels in pain-producing foci in nerve membranes. It is a primary amine analog of lidocaine and can be used for the treatment of tinnitus.

Suppresses ventricular ectopic activity.
Suitable for laboratory centrifugation and storage.

Pricing & Availability

4,860

Medchemexpress LLC Buspirone hydrochloride | 33386-08-2 | 99.99% | 1 ML

Buspirone hydrochloride is a 5-HT1A receptor agonist. It can be used for anxiety and depression research.

5-HT1A receptor agonist
Can be used for anxiety and depression research
Has cytotoxic effect in lymphocytes (0-400 μg/mL; 6 hours)
Induces ROS formation, MMP collapse, lipid peroxidation, lysosomal damage and elevation of glutathione disulfide (GSSG) (0-180 μg/mL; 0-3 hours; lymphocytes)
Reduces anxiety/depression behaviors in C57BL/6N mice (1-5 mg/kg; i.p. and i.g.; for 5 days)
Restores IS-shifted β-diversity in the gut microbiota in C57BL/6N mice (1-5 mg/kg; i.p. and i.g.; for 5 days)
Reduces TNF-α expression and NF-κB+/Iba1+ cell population in the hippocampus and myeloperoxidase activity and NF-κB+/CD11c+ cell population in the colon in C57BL/6N mice
Reduces the IS- or EC-induced gut proteobacteria population in C57BL/6N mice

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Alcohols and polyols

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Medchemexpress LLC Nevanimibe hydrochloride | 133825-81-7 | MFCD00899568 | 99.5% | 458.08 g/mol | C27H40ClN3O | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Nordoxepin hydrochloride | 2887-91-4 | MFCD00135797 | 99.9% | 301.81 g·mol⁻¹ | C18H20ClNO | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC AMXI-5001 hydrochloride | 00-00-0 | 98.1% | C25H21ClFN5O3 | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Topotecan hydrochloride | 119413-54-6 | MFCD00866235 | 99.9% | 457.91 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ladostigil hydrochloride | 209394-18-3 | 99.9% | 308.80 g/mol | C16H21ClN2O2 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Sri-37330 hydrochloride | 2322245-49-6 | 99.72% | C16H20ClF3N4O2S | 1 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Fadrozole hydrochloride | 102676-31-3 | 99.9% | C14H14ClN3 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC AMXI-5001 hydrochloride | 98.1% | C25H21ClFN5O3 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Abeprazan hydrochloride | 1902954-87-3 | 99.9% | 446.87 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC AMXI-5001 hydrochloride | 98.1% | C25H21ClFN5O3 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC CCG258208 hydrochloride | 98.1% | 488.94 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Gefitinib hydrochloride | 184475-55-6 | 99.8% | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ninhydrin | 485-47-2 | 99.99% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Tocainide hydrochloride | 71395-14-7 | 99.5% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Buspirone hydrochloride | 33386-08-2 | 99.99% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More